are you using sidechain compression for the bassline with the kickdrum.
myself, i do a lot of editing in reason but rarely pre-process the sounds.
i'm using mainly eqs and compression at least for the main sounds (kick+bass, snare) and often layer drumsounds, i'm also using sidechain compression. but it's all not very professional and of course self-taught, so often there's a bit of clipping on my tracks because i don't work precisely enough - and i'm a complete mastering noob, only using shitty maximisers on everything
