When mixing as you go, really think about the volume of an element you bring in. A lot of times I get lost making a sound, a bit, and I kind of forget where it belongs in the mix, so drop the volume and then start turning it up. Get it till it sits right in the mix, then turn it up another bump, like 3-6db. It should be kind of too big and annoying now.
Now start sculpting the sound back. Start taking away the annoying/two big/ringing/too resonant parts. As you whittle the sound down with compression, eq, transient shapers, saturation, you have a good chance of ending up with a sound that sits right in the mix again, and has all of its strengths totally intact, driving/distinguishing the sound in the mix.
tldr:
In the past, I'd bring in a sound, and sit it in the mix, then i'd start trying to make it bigger, better. It's hard. Volume is better, better than everything else, but give the volume to the right parts of your sound.


